Endocrine Abstracts

Background: Emerging evidence shows that diabetes mellitus causes structural and functional alterations in the brain. Recent studies have shown that diabetes may induce reductions in N-acetyl aspartate (NAA) and glutamate concentrations in the cortical grey matter, but few studies have performed the neurochemical profiling of other brain regions in patients with diabetes. Hence, the aim was to investigate brain metabolites in other brain regions of adults with diabetes.<p ...

Background: Gonadal dysgenesis (GD) is a congenital disorder of sex development resulting in gonadal dysfunction caused by a variety of underlying genetic aberrations. Psychiatric morbidity is more common in women with GD in comparison to the general population but whether this is the result of a hormonal disbalance is unknown. However, psychotic symptoms due to abrupt changes in blood estrogen levels have been commonly reported. The aim is to report the first case of a psycho...